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Choice of platelet treat-ment depends on patient characteristics includingtolerance of specific agents or comorbid illness.

testing of all HCM-associated genes in apatient with a familial form of hypertrophic cardiomyopathy), but it can only beused in cases where a speci?c clinical diagnosis exists. As discussed inChapter 2, hepatic biotransformation enzyme activity issubstantially increased in response to treatment orexposure to a variety of chemicals

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