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Incidenceand impact on outcome of streptokinase allergy in the GUSTO-I trial. The usualmanifestations are weakness, fatigue, musclecramps; cardiac arrhythmias are the seriouscomplications.

low activity ismore common in Caucasian than in Asian populations.Catechol O-methyltransferase is unusual in that it exists intwo forms, but both arise from a single gene (i.e., from twotranscription start sites).

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